The project of the Church of la Recoleta Domínica was designed by the Italian architect Eusebio Chelli, who also participated in an important manner in other architectonic projects in Santiago. The temple is somewhat similar to the Church of Saint Pablo Extramuros in Rome, since Chelli also participated in the design of this work. It is one of the most magnificent churches of Santiago given the materials used and the proportions of the interior spaces.

The general structure is made of brickwork with whitewash. The entrance portico of the Church is designed in a classic-style. It is formed by eight columns made of Carrara marble in a Corinthian style, similar to the interior ones and are supported over pedestals that hold a triangular pediment.

The entrance doors made of American oak are completely carved by the Chilean sculptor José Miguel Blanco crowned in a dintel that holds a completely adorned semicircular arch. On both sides there are small panels with moldings decorated with ornamental scallop trims and are embellished with organic motifs.

The interior is organized according to a Basilica-type floor layout of three naves in a post and dintel construction, the central nave is higher than the lateral ones and ends in an apse where the high altar is located. The naves are separated by a series of columns that are crowned in semicircular arches. In the existing spatial difference between the central nave and the lateral ones there are windows that are topped in semicircular arches that run through all the extension of the nave, providing its natural illumination. In the union of the central nave with the apse, there is a great dodecagonal dome made of Oregon pine with a lantern.