Chelli’s work clearly alludes to classical and Renaissance influences on its architecture, both on structure and decoration. Painted in soft shades of yellow and white, the façade, designed and built by Cremonesi, is vertically divided into three parts, highlighting the central part as the main entrance, thanks to Graeco-Latin ornamentation elements. The entrance, crowned with a semicircular arch, bears the following Latin inscription overhead: “HAEC EST DOMUS DEI ET PORTA COELI” (“This is the House of God and the Gate of Heaven”). Decoration refers to the Blessed Sacrament. Furthermore, entrance is sheltered by four majestic Corinthian columns, among which there are two niches also crowned with semicircular arches containing representations of Saint Ignatius that are guarded by angel bas-relieves. The columns support a frieze bearing the Latin inscription “AD MAIOREM DEI GLORIAM” (“For the greater glory of God”). The origin of the phrase is attributed to the founder of the Jesuits, Saint Ignatius of Loyola, who intended it to serve as a cornerstone sentiment of the society’s religious philosophy. Façade is crowned with a triangular pediment that bears Jesus Christ’s monogram, ornamented with vegetal motifs and a cross.

The two towers included in the façade project carried out by Cremonesi are located on both sides of this structure. Towers are divided into two parts. The first one has a parallelepiped shape adorned with architectural motifs, both added columns and pediments and cornices. The upper part has a cylindrical shape with the same kind of decoration in order to maintain a coherent rhythm, crowned with lanterns with the cross symbol. East tower has a four-face clock, manufactured in Bilbao and installed in 1901 by Evaristo Molina. West tower has three bells, two of which were created from the melting of one of the bells adorning the former Church of the Company of Jesus that was destroyed by the big fire.

Inside, the church layout is a three-nave basilica. The highest is the central nave that is crowned with a segmental barrel vault, entirely decorated. Naves are separated by arcades with large pillars supporting intercolumniations of semicircular arches. Difference in height among naves is used as a clerestory with semicircular windows.