The construction of the current Santa Ana church began in 1806 with the design of architect Juan José Goycolea. Previously, four constructions had already been carried out which were destroyed by various earthquakes, its origin being the year 1578.

The building of Juan José Goycolea is projected on a Latin cross floor plan and is of neoclassical style.

Its façade is composed of eight large Doric columns with three access doors in between, the central door is taller and wider than the other two. The tower, built many years later, rises above the central volume and consists of three bodies superimposed from larger to smaller; the first is rectangular with pilasters in the corners and openings in each of its faces; the second is octagonal with semicircular arches on each of the widest faces; the third body, also octagonal, has a clock on each of the wider faces; the tower is topped by a spire and lantern.

The interior of the temple consists of columns and pilasters. Its white walls and barrel vault make the design look very clean and their decoration with moldings is very simple.

Between the columns of the only nave a panel is formed, like a modular sequence, with pilasters and semicircular arches where devotional altars are positioned. The nave is illuminated by the windows provided with horizontal vitreaux with semicircular arch.

The transept and the area of the High Altar are also illuminated with horizontal vitreaux with semicircular arches.