The start of this church is related to the Sisters of Charity of the Good Shepherd, who arrived from France in 1885 and there is an interconnection with the story of the temples of the Good Shepherd, on Rivera Street in the District of Independencia, and the one of Saint Peter, located on Mac Iver Street in downtown Santiago, all initially belonging to this same Congregation.

The first place the Sisters of Charity settled in was in San Felipe, their initial house. A couple of years later they arrived to Santiago, settling in the house on Rivera Street, where the Church of the Good Shepherd is currently found.

Their third house was created in 1888, being open to the community in March 1890. It was Pedro Fernández Concha, whose family was very close to the tasks of the Good Shepherd Sisters, who ceded around 18,900 meters of lands of the El Carmen farm so that the house and the new Church could be built, that afterwards in an official manner was donated by public deed to the Congregation, on January 2, 1901. This transfer happened in parallel with the works fostered in the sector by the Regional Governor Santiago Benjamín Vicuña Mackenna who created the road “Camino de Cintura Oriente” (current Vicuña Mackenna Avenue) and the “Camino de Cintura Sur” (current Matta Avenue), where the temple is located.

Once the refuge house was concluded, the church of the Holy Sacrament was started. Bishop Mariano Casanova presided the ceremony with which the first stone was laid of this work, on November 8, 1891. Pedro Fernández Concha contracted the French architect Emilio Doyère to be in charge of the project.
On September 8, 1896, the temple to the Holy Sacrament was consecrated and inaugurated, through a great and solemn ceremony led by Mariano Casanova and a numerous clergy. Mother María de Saint Agustin de Jesus (Josefa Fernández Concha) was also present, visiting the houses of the Congregation at the request of the Mother General.

According to writings, before starting the celebration and later festivities, a significant number of people in distress and submerged in poverty started to arrive to the place, entering the temple and sitting in places exclusively reserved for guests. One of the sons of Pedro Fernández Concha tells his father of the situation and that there were no more seats available. He, who felt close to the most humble, answered: “The house of God is the house of the poor, I would not make them leave for anything in the world; let the rich sit where they can”. Finally, the “40 hour adoration” marked the end of the celebrations of the temple inauguration.

On the growing increase of people, the construction was started on November 18, 1891 of the section of the “Department for the Repentant” located on the eastern side of the church, adding to the already built section for “distinguished or known people who needed rehabilitation”.

In 1900 the capacity of the Congregation is extended on this land once again, approving the construction of a correctional school, at the expense of the government but in the Good Shepherd lands. It was the Bishop Rafael Fernández Concha (Josefa’s brother) who was in charge of the confession for some time.

On March 9, 1906 the transfer of the Holy Sacrament was done, concluding the embellishment of the temple. However, improvement works started on the monastery facilities: a labor room was added and another for a new dormitory in the Repented Department and the washing room was extended, adjusting it to the new number of people.

The 1985 earthquake left several damages, which is why on the following year it is declared Historical Monument due to “its relevant merits and architectonic quality”. Thus, afterwards in 1996 the remodeling of the temple is approved, restructuring the main tower principal and improving the interior. But, once again the 2010 earthquake leaves damages, which is why today it is closed and there are no religious activities waiting to collect funds to start its restoration. It currently belongs to the Chilean Prison Service, and its institutional temple.